A Review on Atopic Dermatitis: Etiology, Clinical Features, Pathogenesis, Diagnosis, and Various Treatments

Preethi T; C. J. Glady Gloria Grant; Jayaprakash U

Title:
A Review on Atopic Dermatitis: Etiology, Clinical Features, Pathogenesis, Diagnosis, and Various Treatments

Authors:
Jayaprakash U | Preethi T | C. J. Glady Gloria Grant

Cite This Article :

Jayaprakash U | Preethi T | C. J. Glady Gloria Grant "A Review on Atopic Dermatitis: Etiology, Clinical Features, Pathogenesis, Diagnosis, and Various Treatments" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-3, April 2022, pp.1476-1487, URL: https://www.ijtsrd.com/papers/ijtsrd49758.pdf

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Abstract :
Atopic dermatitis is a recurrent, chronic inflammatory skin disease which affects children. Dermatitis is derived from the Greek words "derma" (skin) and "itis" (inflammation). It affects 10-20% of adolescents and 1-3 percent of adults over their lifetime are caused by a complicated interaction between relevant genes, the environment of the host, pharmacological aberrations, and immunological variables. Two primary theories have been postulated. The first theory is that the adaptive immune system is out of balance, and the second is that the skin barrier is impaired. There is no specific test for Atopic dermatitis. Topical or systemic treatments are indicated depending on the severity of the Atopic dermatitis. It includes emmolients, corticosteroids, calcineurin inhibitors, phosphodiesterase 4 inhibitors, biological and wet wrap therapy. Once remission has been achieved, proactive maintenance therapy should be used to limit the number of flare-ups.

Keywords :
Atopic Dermatitis, Filaggrin, Flare-ups, Human monoclonal antibody

Publication Details:

Unique Identification Number : IJTSRD49758

Published In : Volume-6 | Issue-3, April 2022

Page Number(s) : 1476-1487

Publisher Name : IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470

Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

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